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被妖物控制的孤弱少女聂小倩，为给树妖姥姥准备贡品，偶然间遇到上京赶考的书生宁采臣。本性善良的小倩再多次与宁采臣接触后，被期纯真的品质锁打动。宁采臣得知小倩境遇后，请求燕赤霞取回小倩元魄，不料遭到黑山老妖阻拦，从而渡过了一段曲折艰辛从妖到人的经历。最终邪不胜正，宁采臣与聂小倩终成眷属。。Two hundred years after Mary Shelley's novel the brilliant but mad Doctor (Thomas Kretschmann) has sustained his creature and himself over two centuries through genetic experimentation. In present-day America Detective O'Connor (Parker Posey) is investigating a series of horrific murders which leads her to the doctor and his creature. What she uncovers reveals the strange evolu...。